View inside a mouse's brain

View inside a mouse's brain

This short video clip taken in neuroscientist Patrick Drew's lab shows an image stack from an intact mouse brain taken with a two-photon microscope. Blood vessels have been labeled with a red dye, and the green cells are microglia, the immune cells of the brain. The image is approximately 100 micrometers across, roughly the diameter of a human hair, and each frame is 1 micrometer deeper than the next. Using this technique, Drew is able to image spontaneous and sensory-evoked changes in blood flow and volume at the level of single vessels. For more information, see www.rps.psu.edu