Health Shorts: Aging fat cells may signal diabetes

Laboratory studies suggest that aging of fat cells, perhaps because of oxidative stress, may speed up the aging process and lead to the development of diabetes. Researchers were able to reduce age-related changes and improve insulin sensitivity by blocking the activity of tumor suppressor gene p53 in fat tissue.

Another study of visceral fat tissue taken from patients undergoing abdominal surgery found more age-related changes and inflammatory cytokines among persons with diabetes.

[SOURCE: “Aging fat cells implicated in insulin resistance,” Reuters Health, September 4, 2009]

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Last Updated May 20, 2010