Murakami_cryoEM

Murakami_cryoEM

FEI Titan Krios Cryo-electron microscope and image of RNA polymerase

A new cryo-EM study shows that the enzyme that makes RNA from a DNA template (RNA polymerase) is altered to slow the production of ribosomal RNA in the bacteria E. coli. The FEI Titan Krios Cryo-electron microscope at the Penn State Huck Institutes of the Life Sciences (left). Cryo-EM image of the RNA polymerase and DNA complex (greyscale, right) with color insets of the 3-D reconstructions of the RNA polymerase closed complex (top) and the RNA polymerase and promoter complex with DksA (bottom).

IMAGE: Murakami Laboratory, Penn State