population mutations

population mutations

graph on left indicates treated patients with mutations. Graph on right shows population of mutations in bar graph.

(Left) A schematic of drug resistance across a population of patients. Patients with initially sensitive disease (blue) are treated with a drug. Different genetic mutations cause different resistance mutations (red, yellow, and green). (Right) Tallying up the number of patients associated with each resistance allele, some alleles are more common in the clinical population than others.

IMAGE: Scott Leighow, Penn State