An international team, led by Penn State researchers, may have identified genes that could help farmers, especially ones in low- and middle-income countries, breed chickens that can resist one of the biggest disease threats facing poultry today.
Researchers have discovered a gene that drives color differences within a species of bumble bees, helping to explain the highly diverse color patterns among bumble bees.
A pair of Penn State professors will combine different sources of information to more efficiently identify genes involved in disease progression. Ultimately, this work may help to further precision medicine.
A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.
January's Science on Tap event on Jan. 15 features Penn State researchers Jason Rasgon and Jonathan Marks, who will discuss gene editing and its applications, as well as the ethics surrounding it.
A new $2.4 million-dollar program to train graduate students in the area of eukaryotic gene regulation has been established at Penn State.
A gene associated with the learning disorder dyslexia may play a role in athletes’ susceptibility to concussions, according to a study by Penn State and Northwestern University. The pilot study included 87 Division I Penn State football players from 2015 to 2017. Researchers aimed to determine whether a genotype in nine candidate genes predicted the number of previously diagnosed concussions in this group of football players.
Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results. A team of researchers has developed a new framework that can combine three existing methods of finding these large mutations — or structural variants — into a single, more complete picture.
A new study led by researchers at Penn State reveals that the total amount of rare mutations — deletions, duplications or other changes to the DNA sequence — in a person’s genome can explain why individuals with a disease-associated mutation can have vastly different symptoms.
UNIVERSITY PARK, Pa. — A technology designed to improve CRISPR-Cas9 gene editing in mosquitoes and other arthropods succeeds with a high degree of efficiency, while eliminating the need for difficult microinjection of genetic material, according to researchers.
Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.
For more than a century, plant geneticists have been studying maize as a model system to understand the rules governing the inheritance of traits, and a team of researchers recently unveiled a previously unknown mechanism that triggers gene silencing in corn.
In a study of adolescent boys and girls, neuroscientists at Georgetown University Medical Center and Penn State University have found a sex difference in a gene linked to substance use disorders.
A new study explores how herpes simplex virus might change when passed from one individual to another, information that may prove useful in future development of therapeutics and vaccines.
Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.
