Occupied canine parvovirus

Occupied canine parvovirus

3D schematic of canine parvovirus with an antibody attached

The researchers discovered that a location on canine parvovirus (CPV) where dog antibodies bind — called an antibody binding site — overlaps with a location on CPV where the virus attaches to cells — called a receptor binding site — in a fashion that is similar to SARS CoV-2 and influenza viruses. As a result, when antibodies attach to this antibody binding site on the virus, they prevent the virus from then attaching to and infecting cells. The image shows an antibody attached to CPV.

IMAGE: Penn State