CNV Wing and Eye

CNV Wing and Eye

Effect of knocking down CNV genes in eye and wing.

Genes in copy number variant (CNV) regions of the human genome typically associated with neurodevelopment caused defects in both the fly eye (neuronal) and wing (non-neuronal) tissues, although the severity did not correlate between the two tissues. CNV genes globally affect biological processes important for development, leading to different effects across multiple organs.

IMAGE: Girirajan Laboratory, Penn State