Girirajan6-2018_Figure1

Girirajan6-2018_Figure1

Illustration of chromosome 16 showing the 14 fly counterparts of the 25 human genes

Illustration of chromosome 16 showing the 14 fly counterparts of the 25 human genes located in a deletion on the chromosome that is associated with autism risk. Researchers used RNA interference (RNAi) to reduce the expression of these genes individually and in tandem to test how the interactions of these genes modulate neurodevelopmental symptoms associated with the deletion. Interactions between genes that either enhance or suppress the affect of reduced expression are shown by red or blue lines.

IMAGE: Girirajan Laboratory, Penn State