Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.
Big, small, broad, narrow, long or short, turned up, pug, hooked, bulbous or prominent, humans inherit their nose shape from their parents, but ultimately, the shape of someone's nose and that of their parents was formed by a long process of adaptation to our local climate, according to an international team of researchers.
Cutting-edge research at Penn State College of Medicine and the Penn State Colorectal Diseases Biobank is revealing how genetics play a role in treating colorectal cancer.
Penn State graduate student Olivier Noel is only 28 years old, but he’s already changing the face of genetics research.
Thomas J. Gould has been named head of the Department of Biobehavioral Health in the College of Health and Human Development at Penn State. In this role, he will hold the Jean Phillips Shibley Professorship of Biobehavioral Health. Gould joins Penn State, effective July 1, after serving as professor of psychology and director of the program in neuroscience at Temple University.
The Penn State Institute for CyberScience (ICS) has awarded $25,000 to Tao Yao, associate professor in the Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, and his team of researchers for their project titled, “High-Dimensional Data Analysis for Parkinson’s Disease.”
A faster, less expensive method has been developed and used to learn the DNA sequence of the male-specific Y chromosome in the gorilla. The research reveals that a male gorilla’s Y chromosome is more similar to a male human’s Y chromosome than to a chimpanzee’s. The technique works for any species, so it can be used to study male infertility disorders and male-specific mutations. It also can aid in conservation efforts. "Surprisingly, we found that in many ways the gorilla Y chromosome is more similar to the human Y chromosome than either is to the chimpanzee Y chromosome," said Kateryna Makova, the Francis R. and Helen M. Pentz Professor of Science at Penn State and one of two corresponding authors of the paper.
Jessica Petko, assistant professor of biology at Penn State York, will be the featured speaker at a faculty colloquium on Feb. 10. The program, at 12:10 p.m. in 113 John J. Romano Administration Building, is free and open to the public.
Idan Shalev, assistant professor in the Department of Biobehavioral Health at Penn State, is a 2015 recipient of the Rising Star Award, presented by the Association for Psychological Science. Shalev has been recognized for his innovative work in genetic markers of stress and aging.
"Finding Your Roots," an innovative new school curriculum that utilizes personalized genealogy and genetics to teach science and health to disadvantaged and minority students, has received $659,000 in grants from Robert Wood Johnson Foundation and National Science Foundation.
Penn State Law Associate Dean for Research David H. Kaye spoke on Capitol Hill March 19 regarding the collection and use of DNA evidence at a panel hosted by Congresswoman Louise M. Slaughter and Senator Elizabeth Warren.
Children with autism have increased levels of genetic change in regions of the genome prone to DNA rearrangements, so-called "hotspots," according to a research discovery to be published in the print edition of the journal Human Molecular Genetics. The research indicates that these genetic changes come in the form of an excess of duplicated DNA segments in hotspot regions and may affect the chances that a child will develop autism -- a behavioral disorder that affects about 1 of every 88 children in the United States, according to the Centers for Disease Control. The research collaboration was led by a team from Penn State's Department of Biochemistry and Molecular Biology.
UNIVERSITY PARK, Pa. -- A free public lecture titled "Genetics of Obesity and Weight Loss" will take place at 11 a.m. Feb. 16, in 100 Thomas Building. The speaker will be Glenn S.
A free public lecture titled "Bringing Genomic Medicine into Focus" will take place at 11 a.m. on Feb. 2, in 100 Thomas Building on the Penn State University Park campus. The speaker will be Eric Green, the director of the National Human Genome Research Institute at the U.S. National Institutes of Health.
A free public lecture titled "Life's Little Problem: Determinism Versus Chance in the Complex Ways of Genomes" will take place on 26 January 2013 at 11:00 a.m. in 100 Thomas Building on the Penn State University Park campus. The speaker will be Kenneth M. Weiss, Evan Pugh Professor of Biological Anthropology and Genetics at Penn State University.
The event is the second of six lectures in the 2013 Penn State Lectures on the Frontiers of Science, a free minicourse for the general public with the theme "Your Genes: How They Contribute to Who You Are." No registration is required. The lectures take place on six consecutive Saturday mornings from 11:00 a.m. to about 12:30 p.m. in 100 Thomas Building.