Grant to fund study of infection prevention in prostate biopsy

Penn State College of Medicine’s Dr. Jay Raman has received one of 11 national Clinical Excellence Grants from the CareFusion Foundation. This $50,000 grant is designed to develop and share infection prevention best practices.

Raman’s study will look at the use of a topical antiseptic application prior to biopsy of the prostate with the goal of reducing infectious complications following the procedure. Currently, only oral antibiotics are given at the time of the procedure, which requires at least 12 different pricks of the needle into the prostate. However, bacteria resistance to these oral antibiotics is increasing and contributing to patient morbidity, longer hospitalization, admissions to the intensive care unit, and overall greater costs. This clinical study at Penn State Milton S. Hershey Medical Center will quantify bacteria levels in the blood and urine prior to and after surgery after the use of the topical antiseptic. This study may present an innovative strategy to prevent infections after prostate biopsy.

Prostate cancer is the most common cancer in men and the second leading cause of male cancer-related deaths. At least 241,000 men were estimated to be diagnosed with prostate cancer last year, with 28,000 deaths.

“Infectious complications after prostate biopsy are an increasing problem with significant consequences for the patient and health care system,” Raman said. “This study presents an opportunity to address this health concern using a novel, relatively inexpensive strategy. The support from the CareFusion foundation reflects a true commitment to support research geared towards infection prevention practices.”

Raman is an associate professor of surgery. His clinical practice and research focus are on cancer diagnosis and therapies for patients with urologic malignancies (particularly the prostate). Much of his recent work seeks to reduce infectious complications related to the ultrasound guided prostate biopsy procedure.

Established in 2009, the CareFusion Foundation creates and supports opportunities to improve the safety and cost of health care.

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Last Updated May 30, 2013