John Lis presents the Simpson Lecture on Oct. 18

John T. Lis, the Barbara McClintock Professor of Molecular Biology and Genetics at Cornell University, will present the 2010-11 Robert T. Simpson Memorial Lecture in Molecular Medicine at 4 p.m. on Monday, Oct. 18, in 101 Althouse Laboratory on the Penn State University Park campus. In this free public lecture, titled "New Views of Local and Genome-wide Transcription Regulation In Vivo," Lis will explore how genes are turned on and off. The lecture is sponsored by the Department of Biochemistry and Molecular Biology.

Using fruit fly genes, Lis's research group studies the structure of chromatin -- DNA packaged into bundles -- and the mechanisms of gene transcription and regulation. The group is exploring its findings using existing and new genome-wide technology developed by the laboratory, including the global nuclear run-on assay (GRO-seq) recently developed by the group. Lis's research has been supported, in part, by a National Institutes of Health MERIT Award.

Lis joined the faculty at Cornell in 1978. He earned a doctorate at Brandeis University in 1975 a bachelor's degree at Fairfield University in 1970.

The Robert T. Simpson Lectureship honors Robert T. Simpson and is made possible through donations from his family, friends, colleagues and associates. Simpson was an international leader for more than 35 years in research on chromatin, a fundamental component of chromosomes, and its role in gene regulation. Simpson worked at the National Institutes of Health from 1970 until 1995, when he became the Verne M. Willaman professor of molecular biology at Penn State University. His addition to Penn State in 1995 is considered to have placed Penn State and the Department of Biochemistry and Molecular Biology at the forefront of chromatin research and to have greatly enhanced Penn State's research and educational missions.


Last Updated September 29, 2010