6/3/13Diseases such as tuberculosis, anthrax, and shigellosis -- a severe food-borne illness -- eventually could be treated with an entirely new and more-effective kind of antibiotic, thanks to a team of scientists led by Kenneth Keiler, an associate professor of biochemistry and molecular biology at Penn State. The team describes 46 previously untested molecules that target and disrupt an important step in the process of protein synthesis in bacteria, thereby making the bacteria incapable of replicating. This important step, known as "trans-translation," is a quality-control mechanism that is found in all species of bacteria. More information is online at science.psu.edu/news-and-events/2013-news/Keiler5-2013.